What is the route of administration for diazepam?
What is the route of administration for diazepam?
Diazepam is available in multiple formulations, including oral tablets, intramuscular injections (IM), intravenous injection (IV), or rectal gel. Oral tablets have a more reliable absorption and controlled release when compared to IM.
How do you take diazepam 5mg?
Adults—10 milligrams (mg) 3 or 4 times for the first 24 hours, then 5 mg 3 to 4 times per day as needed. Older adults—At first, 2 to 2.5 mg 1 or 2 times a day. Your doctor will gradually increase your dose as needed. Children—Use and dose must be determined by your doctor.
What is diazepam 5mg used for?
Diazepam is used to treat anxiety, alcohol withdrawal, and seizures. It is also used to relieve muscle spasms and to provide sedation before medical procedures. This medication works by calming the brain and nerves. Diazepam belongs to a class of drugs known as benzodiazepines.
Is diazepam given IM or IV?
Diazepam may be administered intravenously or intramuscularly (deep into the muscle). However, absorption following I.M. administration is slow and erratic; thus, this route of administration should be avoided if possible.
How do you prepare diazepam injections?
Dissolve the diazepam and benzoic acid in the solution. Slowly add Sterile Water for Injection to a volume of 75 to 80 mL. Add the sodium benzoate and mix until dissolved; then add the sodium hydroxide solution or hydrochloric acid to adjust the pH to the range of 6.2 to 6.9.
How long does it take for diazepam 5mg to work?
How long does diazepam take to start working? Diazepam starts to work very quickly in your body, and you should get calming effects within two hours of taking it.
How long before bed should you take diazepam?
Some people may only have to take diazepam for one day, for instance before they have an operation. You should not normally be prescribed diazepam for more than four weeks. If you are taking diazepam to help you sleep, you should take it just before bedtime. Diazepam can be taken before or after food.
Can I give diazepam intramuscularly?
Method of administration Diazepam Injection BP may be given IV injection, IM injection, or by IV infusion. The absorption from IM injection of diazepam may be variable, particularly for the gluteal muscles, and therefore the IM route of administration should only be used if IV administration is not possible.
How do you use a diazepam syringe?
Bend upper leg forward to expose rectum. A) Separate buttocks. B) Gently insert lubricated syringe into rectum up to the rim on the syringe. Count to 3 as you slowly push plunger until it stops.
How do you dilute diazepam injections?
However, if in some circumstances it is necessary to administer diazepam as an infusion, it is recommended that it be diluted in dextrose 5% in water, normal saline, Ringer’s injection or lactated Ringer’s injection to a dilution of at least 1:40 and used within 6 hours or to a dilution of 1:50 and used within 24 hours …
How long does diazepam 5mg tablets take to work?
When taken orally, people usually begin to feel the effects 15 to 60 minutes after ingestion. Rectal gel may be used for those who are experiencing seizures and begins working quickly after administration.