What is flumazenil used for?
What is flumazenil used for?
Flumazenil injection is indicated for a complete or partial reversal of the sedative effects of benzodiazepines in conscious sedation and general anesthesia in the adult and pediatric populations.
What are the side effects for flumazenil?
What are the side effects of Flumazenil (Romazicon)?
- weak or shallow breathing;
- ongoing drowsiness;
- confusion, agitation, tremors, dizziness;
- chest pain and severe dizziness, rapid pulse, fast or pounding heartbeats; or.
- a light-headed feeling, like you might pass out.
What is another name for flumazenil?
Flumazenil is sold under a wide variety of brand names worldwide like Anexate, Lanexat, Mazicon, Romazicon.
How long does it take flumazenil to work?
The 1-minute wait between individual doses in the dose-titration recommended for general clinical populations may be too short for high-risk patients. This is because it takes 6 to 10 minutes for any single dose of flumazenil to reach full effects.
How effective is flumazenil?
By both observer and patient alertness ratings, patients receiving flumazenil appeared significantly more alert than placebo patients at 5, 15, 30, and 60 minutes following reversal. After reversal the flumazenil group had significantly higher scores than the placebo group at all intervals through 60 minutes.
When do you take flumazenil?
Flumazenil is used to reverse the effects of a benzodiazepine (BENZ-oh-dye-AYZ-e-peen) sedative such as Valium, Versed, Xanax, Tranxene, and others. Flumazenil is used to help you wake up after a surgery or medical procedure in which a benzodiazepine was used as a sedative.
How much flumazenil do I take?
The recommended starting dose is 200 micrograms administered intravenously over 15 seconds. If the required level of consciousness is not obtained within 60 seconds, a further dose of 100 micrograms can be injected and repeated at 60-second intervals, up to a maximum dose of 1000 micrograms.
When should you take flumazenil?
Flumazenil is used to help you wake up after a surgery or medical procedure in which a benzodiazepine was used as a sedative. Flumazenil is also used to treat benzodiazepine overdose in adults.
Why is flumazenil not recommended?
Flumazenil lowers the seizure threshold and may lead to life-threatening seizures. It should be avoided or used with extreme caution in settings of benzodiazepine dependence, seizure disorder, cyclic antidepressant overdose, and elevated intracranial pressure.
Does flumazenil increase blood pressure?
Flumazenil improved the consciousness level from 6.7+/-2.0 to 8.9+/-1.6 and induced transient elevations in heart rate, blood pressure, systolic pulmonary artery pressure, and pulmonary artery occlusion pressure.