What is a pulmonary homograft?

Published by Anaya Cole on

What is a pulmonary homograft?

Pulmonary homografts consist of the muscle shelf, pulmonary valve, and proximal pulmonary artery harvested from a human cadaver. They are prepared fresh with antibiotic solution, or cryopreserved, and have proven useful in the reconstruction of both the right and left ventricular outflow tracts.

What is the difference between homograft and autograft?

The autograft technique harvests the patient’s own pulmonary valve, which is then sewn into the aortic position, and a pulmonary homograft is sewn into the pulmonary position. Homograft technique prepares valves from human cadavers.

What is a homograft surgery?

A homograft is an aortic or pulmonic valve that has been removed from a donated human heart, preserved, antibiotic-treated, and frozen under sterile conditions. A homograft may be used to replace a diseased aortic valve, or it may be used to replace the pulmonic valve during the Ross procedure.

What is a homograft root replacement?

Aortic homograft root replacement is a type of heart surgery in which the root of the aorta is removed and replaced with a human tissue graft from a donated heart. The aortic root is the portion of the aorta containing the aortic valve, connecting the aorta to the left ventricle of the heart.

What is a homograft conduit?

Valved conduits often correct the blood flow of congenital heart disease by connecting the right ventricle to the pulmonary artery (RV-PA). The homograft valved conduit was invented in the 1960s, but its wide application is limited due to the lack of effective sterilization and preservation methods.

Is allograft and homograft the same thing?

allograft, also called allogeneic transplant, homograft, in medical procedures, the transfer of tissue between genetically nonidentical members of the same species, although of a compatible blood type.

Are allograft and homograft the same?

Isograft refers to tissue transplanted between genetically identical twins. An allograft (termed homograft in older texts) is tissue transplanted between unrelated individuals of the same species. A xenograft (termed heterograft in older texts) is tissue transplanted between individuals of different species.

How long do pulmonary conduits last?

Most surgically implanted valves or conduits will last 10-20 years before they wear out, become obstructed, or lose efficiency.

What is a pulmonary conduit?

A pulmonary conduit is a tube that connects the heart to the lungs. These CHD patients may need a device like the Melody™ transcatheter pulmonary valve when their surgical valve or conduit needs replacement.

What is the difference between a pig valve and a cow valve?

Unlike a pig valve replacement, a cow valve uses the tissue of the cow’s heart – not the actual heart valve structure itself. The size of an actual cow valve is too large compared to a human heart valve. A cow valve would not fit in a human heart.

Are TAVR valves mechanical or bioprosthetic?

Valve-in-valve TAVR: Many replacement valves that people receive are made from animal tissue (bioprosthetic). These tissue valves can break down or fail over time.

What is the difference between TAVR and Savr?

Surgical aortic valve replacement (SAVR) has been the standard practice for treating severe, symptomatic AS, but recently new treatment options have emerged. Transcatheter aortic valve replacement (TAVR) is now an established treatment option in patients at high surgical risk.