What is a balloon cell nevus?
What is a balloon cell nevus?
Balloon cell nevi are rare, benign melanocytic tumors that may involve the conjunctiva, choroid, and skin. In the ocular adnexa they typically present as raised and mobile hyperpigmented masses. Histologically, balloon cell nevi consist of large cells forming nests that usually lack melanin pigment.
What is a Nevoid melanoma?
English. Nevoid melanoma is a type of skin cancer. It begins when the melanocytes in the skin grow out of control and form tumors. Melanocytes are the cells responsible for making melanin, the pigment that determines the color of the skin.
What does HMB-45 stand for?
Human Melanoma Black
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors. The antibody was generated to an extract of melanoma.
How common is Nevoid melanoma?
Nevoid melanoma, a rare subtype of melanoma, is easily misdiagnosed as a benign nevus. It is estimated that the prevalence of nevoid melanoma is no more than 0.5% of all melanomas reported.
Can a Spitz nevus turn cancerous?
Very few atypical Spitz tumors progress to melanoma and lead to serious health risks, especially when diagnosed and treated early. A suspicious Spitz nevus is usually removed by a doctor while it is still benign. If an atypical Spitz tumor becomes cancerous, it is called a Spitzoid melanoma.
Can a Spitz nevus be removed?
Most of the time, they are watched over time for changes. Measuring the mole’s size and taking photographs of it will help the doctor monitor for changes in size, color, and shape. Spitz nevi can be removed surgically. Surgical removal is recommended for Spitz nevi with concerning features or changes.
Can a benign nevi become malignant?
No. A dysplastic nevus is more likely than a common mole to become cancer, but most do not become cancer.
What is vimentin positive?
In conclusion, vimentin-positive gastric cancer was associated with the highly invasive phenotype of advanced gastric cancer, especially with scirrhous type of gastric carcinoma. Vimentin may play an important role in the metastasis of gastric carcinoma.
What does S 100 positive mean?
S-100 protein (S-100B) is the most widely used marker for peripheral nerve sheath tumors. Although S-100 protein is positive in all benign Schwann cell tumors, this marker shows relatively low sensitivity for MPNST (at most, around 50%).